Protein Folding
Requests for study
ProteoBioChip is a group of graduates in engineering at Padua who created a mathematical model for the analysis of organic molecules. As data source we use the Protein Data Bank and from which we derive the parameters of dynamic models. The set of PDB is divided into two heterogeneous groups. The first group is used to derive the parameters, while the validation of the mathematical model is performed using the second set of PDB data. At this stage of development we are available to perform analysis of molecules of interest to test the potential of this software. We are aware of the difficulty of computational and our limited human resources, but unlike the applications that are developing in these years, we are following a path of simulation that allows a faster calculation of the development and behavior of the protein in question. We look forward to the opportunity to leverage our software in practical situations. We offer the software engineering and our potential partners could provide the technology for experimental research results. In this way we refine the calculations and our co-worker would be able to have a computerized survey of the molecules studied.
We are pleased to offer you one of our processed.
Currently we are all engaged in work activities that have unfortunately taken a different path from our idea, but we will definitely willing to sacrifice all our free time to reach a solution. We believe that protein folding is the biggest challenge of this century and which will mark the development of technology for our future. In recent years we have seen the decline of the development of silicon technology upon which our chip is no longer possible to increase the density of integration on silicon. The silicon and all current electronic techniques have reached the physical limit because the modern microprocessor play the card of the complexity architecture and inherent speed of processing. In short you try to refine the technique and not the technology.
It 'time to change the technology to work at the atomic level, in order to do this there is the need to work with the molecules. To create complex models and desired features you need molecules developed at will and controlled in their behavior.
The molecules with the most potential are the proteins that's why the engineers as we are studying the dynamic behavior of proteins and their folding.
In addition to the development of the simulator of the protein and the subsequent creation of the proteins produced, there is a need to understand what happens at the molecular level. The idea is to use silicon as a marginal component and exploit the ability to interact with proteins of weak electric fields to interface the applications behave with the outside world. The silicon would be required to interact with proteins which would be exploited to create a computational architecture. The heart of the modern computer would become a complex of proteins and the chip would be used only as an electronic interface.
Hence the name we created: ProteoBioChip.
  • Proteo to indicate the contribution of protein
  • Bio to indicate that the process is the basis of life
  • Chip not to forget that all our current technology is based on the economic success of the silicon.
Would think of as our current way of living without the silicon and Think of it as it will with ProteoBioChip.
Surely the technological development will follow this direction, many already know, glorious and fortunate will be the first to do it ...

Ing. Francesco Barbieri

Protein folding

  • Analysis of dynamics of organic molecules
  • Study of interaction between various organic molecules
  • Study of molecules of pharmaceutical interest (determined by software analysis of similarities)
  • Engineering of molecules with specific biological functions
  • Determination of pathological dynamics of molecules